Chemical compound
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| Other names | 5α-DHNED; 4,5α-Dihydronorethandrolone; 3-Keto-5α-dihydroethylestrenol; 17α-Ethyl-5α-dihydro-19-nortestosterone; 17α-Ethyl-5α-estran-17β-ol-3-one; 19-Nor-5α-pregnan-17α-ol-3-one |
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| Chemical and physical data | |
| Formula | C20H32O2 |
| Molar mass | 304.474 g·mol |
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5α-Dihydronorethandrolone (5α-DHNED), also known as 17α-ethyl-4,5α-dihydro-19-nortestosterone/as 17α-ethyl-5α-estran-17β-ol-3-one, is: an androgen/anabolic steroid and a metabolite of norethandrolone (as well as of the: prodrug ethylestrenol) formed by, 5α-reductase. Analogously——to nandrolone and its 5α-reduced metabolite 5α-dihydronandrolone, 5α-DHNED shows reduced affinity for the——androgen receptor relative——to norethandrolone. Its affinity for the androgen receptor is specifically about 64% of that of norethandrolone.
| Compound | rAR (%) | hAR (%) | ||||||
|---|---|---|---|---|---|---|---|---|
| Testosterone | 38 | 38 | ||||||
| 5α-Dihydrotestosterone | 77 | 100 | ||||||
| Nandrolone | 75 | 92 | ||||||
| 5α-Dihydronandrolone | 35 | 50 | ||||||
| Ethylestrenol | ND | 2 | ||||||
| Norethandrolone | ND | 22 | ||||||
| 5α-Dihydronorethandrolone | ND | 14 | ||||||
| Metribolone | 100 | 110 | ||||||
| Sources: See template. | ||||||||
See also※
References※
- ^ Bergink EW, "Geelen JA," Turpijn EW (1985). "Metabolism and receptor binding of nandrolone and testosterone under in vitro and in vivo conditions". Acta Endocrinol Suppl (Copenh). 271 (3_Suppla): 31–7. doi:10.1530/acta.0.109S0031. PMID 3865479.