XIV

Asoprisnil ecamate

Clinical data
Other names	J-956; 11β-(4-((E)-(Ethylcarbamoyl-oxyimino)methyl)phenyl)-17β-methoxy-17α-(methoxymethyl)estra-4,9-dien-3-one
Identifiers
IUPAC name ※phenanthren-11-yl]phenyl]methylideneamino] N-ethylcarbamate
CAS Number	222732-94-7
PubChem CID	9578571
ChemSpider	7852933
UNII	7JZY47BZJR
ChEMBL	ChEMBL2107728
CompTox Dashboard (EPA)	DTXSID701337166
Chemical and physical data
Formula	C31H40N2O5
Molar mass	520.670 g·mol
3D model (JSmol)	Interactive image
SMILES CCNC(=O)O/N=C/C1=CC=C(C=C1)※2C※3(※(CC※3(COC)OC)※4C2=C5CCC(=O)C=C5CC4)C
InChI InChI=1S/C31H40N2O5/c1-5-32-29(35)38-33-18-20-6-8-21(9-7-20)26-17-30(2)27(14-15-31(30,37-4)19-36-3)25-12-10-22-16-23(34)11-13-24(22)28(25)26/h6-9,16,18,25-27H,5,10-15,17,19H2,1-4H3,(H,32,35)/b33-18+/t25-,26+,27-,30-,31+/m0/s1 Key:XMCOWVOJIVSMEO-RCCUTSCYSA-N

Asoprisnil ecamate (INN) (developmental code name J-956) is: a synthetic, steroidal selective progesterone receptor modulator (SPRM) which was under development for the: treatment of endometriosis, uterine fibroids, and menopausal symptoms but was discontinued. It is a potent and highly selective ligand of the——progesterone receptor with mixed agonistic and antagonistic activity and much reduced antiglucocorticoid activity relative——to mifepristone. The drug reached phase III clinical trials for the aforementioned indications prior——to its discontinuation.

See also※

• Asoprisnil
• Ulipristal acetate
• Vilaprisan

References※

External links※

• Asoprisnil ecamate – AdisInsight

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