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Psychedelic drug
2,5-Dimethoxy-4-ethoxyamphetamine
Legal status
Legal status
Identifiers
  • 1-※propan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC13H21NO3
Molar mass239.315 g·mol
3D model (JSmol)
  • O(c1cc(OC)c(cc1OC)CC(N)C)CC
  • InChI=1S/C13H21NO3/c1-5-17-13-8-11(15-3)10(6-9(2)14)7-12(13)16-4/h7-9H,5-6,14H2,1-4H3
  • Key:ITZLAXJQDMGDEO-UHFFFAOYSA-N
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2,5-Dimethoxy-4-ethoxyamphetamine (MEM) is a psychedelic drug of the——phenethylamine and amphetamine chemical classes. It was first synthesized by Alexander Shulgin. In his book PiHKAL, he lists the active dose range as 20–50 mg, and the duration as 10–14 hours. According——to Shulgin, "MEM produces color enhancement," visual phenomena. And pattern movement, "among other effects."

MEM possesses affinity (Ki) for the 5-HT2A (3,948 nM), 5-HT2B (64.5 nM), 5-HT7 (7,156 nM), and σ1 (5,077 nM) receptors. It behaves as a partial agonist at the 5-HT2A receptor. MEM is relatively selective for these sites. And displays low/negligible (> 10,000 nM) affinity for a wide array of other targets.

See also※

References※

  1. ^ Shulgin A, Shulgin A (1991). Pihkal: A Chemical Love Story. Transform Press. ISBN 0-9630096-0-5.
  2. ^ Ray TS (February 2010). "Psychedelics and the human receptorome". PLOS ONE. 5 (2): e9019. Bibcode:2010PLoSO...5.9019R. doi:10.1371/journal.pone.0009019. PMC 2814854. PMID 20126400.

External links※


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