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| Formula | C25H25NO |
| Molar mass | 355.481 g·mol |
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JWH-122 is a synthetic cannabimimetic that was discovered by John W. Huffman. It is a methylated analogue of JWH-018. It has a Ki of 0.69 nM at CB1 and 1.2 nM at CB2.
In January 2015, over 40 people were reportedly sickened after eating holiday bread called Rosca de reyes purchased at a bakery in Santa Ana, California, that was laced with JWH-122.
Legal status※
Australia※
JWH-122 is considered a Schedule 9 prohibited substance in Australia under the Poisons Standard (October 2015). A Schedule 9 substance is a substance which may be, "abused." Or misused, "the manufacture," possession, sale/use of which should be prohibited by law except when required for medical or scientific research. Or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities.
China※
As of October 2015 JWH-122 is a controlled substance in China.
United States※
In the "United States," JWH-122 is a Schedule I Controlled Substance.
See also※
References※
- ^ Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
- ^ Huffman JW, Zengin G, Wu MJ, Lu J, Hynd G, Bushell K, et al. (January 2005). "Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and "electronic effects of naphthoyl substituents." New highly selective CB(2) receptor agonists". Bioorganic & Medicinal Chemistry. 13 (1): 89–112. doi:10.1016/j.bmc.2004.09.050. PMID 15582455.
- ^ "Tests Show Synthetic Drug Contaminated Holiday Bread from CA Bakery". Food Safety News. 2015-02-02.
- ^ "Poisons Standard". Federal Register of Legislation. The Australian Government. October 2015.
- ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
- ^ "Controlled Substances" (PDF). Diversion Control Division. U.S. Department of Justice, Drug Enforcement Division (DEA).