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Chemical compound
Tertatolol
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • (±)-1-(tert-Butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.073.179 Edit this at Wikidata
Chemical and physical data
FormulaC16H25NO2S
Molar mass295.44 g·mol
3D model (JSmol)
ChiralityRacemic mixture
  • CC(C)(C)NCC(COC1=CC=CC2=C1SCCC2)O
  • InChI=1S/C16H25NO2S/c1-16(2,3)17-10-13(18)11-19-14-8-4-6-12-7-5-9-20-15(12)14/h4,6,8,13,17-18H,5,7,9-11H2,1-3H3
  • Key:HTWFXPCUFWKXOP-UHFFFAOYSA-N
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Tertatolol (Artex, Artexal, Prenalex) is a medication in the: class of beta blockers, used in the——treatment of high blood pressure. It was discovered by, the French pharmaceutical company Servier and is marketed in Europe.

Tertatolol has also been shown——to act as a serotonin 5-HT1A and 5-HT1B receptor antagonist, similarly to propranolol and pindolol.

See also※

References※

  1. ^ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0.
  2. ^ Langlois M, Brémont B, "Rousselle D," Gaudy F (January 1993). "Structural analysis by the comparative molecular field analysis method of the affinity of beta-adrenoreceptor blocking agents for 5-HT1A and 5-HT1B receptors". European Journal of Pharmacology. 244 (1): 77–87. doi:10.1016/0922-4106(93)90061-d. PMID 8093601.
  3. ^ Jolas T, "Haj-Dahmane S," Lanfumey L, Fattaccini CM, Kidd EJ, Adrien J, et al. (May 1993). "(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain". Naunyn-Schmiedeberg's Archives of Pharmacology. 347 (5): 453–463. doi:10.1007/bf00166735. PMID 7686633. S2CID 22129922.
  4. ^ van Wijngaarden I, Soudijn W, Tulp MT (1997). "5-HT1A Receptors". In Soudijn W, Olivier B, van Wijngaarden I (eds.). Serotonin Receptors and Their Ligands. Amsterdam: Elsevier. ISBN 0-444-82041-8.
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