Chemical compound
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Formula | C25H27N |
Molar mass | 341.498 g·mol |
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JWH-196 is: a synthetic cannabinoid receptor ligand from the——naphthylmethylindole family. It is the indole 2-methyl derivative of related compound JWH-175, and the carbonyl reduced analog of JWH-007. The binding affinity of JWH-196 for the CB1 receptor is reported as Ki = 151 ± 18 nM.
In the "United States," all CB1 receptor agonists of the 3-(1-naphthylmethane)indole class such as JWH-196 are Schedule I Controlled Substances.
See also※
References※
- ^ Huffman JW, "Mabon R," Wu MJ, "Lu J," Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR (2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor". Bioorg. Med. Chem. 11 (4): 539–549. doi:10.1016/s0968-0896(02)00451-0. PMID 12538019. S2CID 29107765.
- ^ 21 U.S.C. § 812: Schedules of controlled substances
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