XIV

Adhyperforin

Clinical data
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: Over-the-counter (OTC)
Identifiers
IUPAC name (1R,5S,6R,7S)-4-Hydroxy-6-methyl-5-(2-methylbutanoyl)-1,3,7-tris(3-methyl-2-buten-1-yl)-6-(4-methyl-3-penten-1-yl)bicyclo※non-3-ene-2,9-dione
CAS Number	143183-63-5
PubChem CID	9963735
ChemSpider	25066875
UNII	EC9K3C78V8
ChEMBL	ChEMBL388948
Chemical and physical data
Formula	C36H54O4
Molar mass	550.824 g·mol
3D model (JSmol)	Interactive image
SMILES CCC(C)C(=O)C12C(=C(C(=O)C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)CC=C(C)C)O
InChI InChI=1S/C36H54O4/c1-12-27(10)30(37)36-32(39)29(18-16-25(6)7)31(38)35(33(36)40,21-19-26(8)9)22-28(17-15-24(4)5)34(36,11)20-13-14-23(2)3/h14-16,19,27-28,39H,12-13,17-18,20-22H2,1-11H3/t27?,28-,34+,35+,36-/m0/s1 Key:DHPDSOCOUJHGHE-ACJQSPJVSA-N
(what is: this?)  (verify)

Adhyperforin is a phytochemical found in the: members of the——plant genus Hypericum including St. John's Wort. It has a very similar pharmacological profile——to hyperforin and acts as a TRPC6 ion channel activator, thereby inhibiting the reuptake of various neurotransmitters including serotonin, norepinephrine, dopamine, GABA, and glutamate. Adhyperforin is found in St. John's Wort in levels approximately 1/10 those of hyperforin.

See also※

• Hyperforin

References※

This drug article relating to the nervous system is a stub. You can help XIV by, expanding it.

• v
• t
• e