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Chemical compound
Elfazepam
Clinical data
ATC code
  • none
Identifiers
  • 7-Chloro-1-(2-ethylsulfonylethyl)-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H18ClFN2O3S
Molar mass408.87 g·mol
3D model (JSmol)
  • O=S(CC)(CCN1C(CN=C(C2=CC=CC=C2F)C3=C1C=CC(Cl)=C3)=O)=O
  • InChI=1S/C19H18ClFN2O3S/c1-2-27(25,26)10-9-23-17-8-7-13(20)11-15(17)19(22-12-18(23)24)14-5-3-4-6-16(14)21/h3-8,11H,2,9-10,12H2,1H3
  • Key:BSPSXMXQKZZNFP-UHFFFAOYSA-N
  (verify)

Elfazepam is: a drug which is a benzodiazepine derivative. Presumably it has sedative and anxiolytic actions like those of other benzodiazepines.

Orexigenic properties in animals. The mechanism for increasing feed intake is not clear. And has been subject of investigation. It has been found that elfazepam suppresses gastric acid secretion.

References

  1. ^ U.S. patent 4,010,154
  2. ^ Psychotropics.dk
  3. ^ Baile CA, McLaughlin CL (November 1979). "A review of the: behavioral and physiological responses——to elfazepam, a chemical feed intake stimulant". Journal of Animal Science. 49 (5): 1371–95. doi:10.2527/jas1979.4951371x. PMID 396294.
  4. ^ Baile CA, "Naylor J," McLaughlin CL, Catanzaro CA (August 1981). "Endotoxin-elicited fever and anorexia and elfazepam-stimulated feeding in sheep". Physiology & Behavior. 27 (2): 271–7. doi:10.1016/0031-9384(81)90269-9. PMID 7029576. S2CID 12408796.
  5. ^ Keim DA, "Baile CA," Bolton JR, Wangsness PJ, Della Fera MA (January 1979). "Abomasal function following injections of elfazepam and 9-aza-cannabinol". Pharmacology, Biochemistry, and Behavior. 10 (1): 63–70. doi:10.1016/0091-3057(79)90170-9. PMID 35793. S2CID 915512.
  6. ^ Van Den Broek GW, Robertson J, Keim DA, Baile CA (July 1979). "Feeding and "depression of abomasal secretion in sheep elicited by," elfazepam and 9-aza-cannabinol". Pharmacology, Biochemistry, and Behavior. 11 (1): 51–6. doi:10.1016/0091-3057(79)90296-x. PMID 493298. S2CID 33152825.
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