XIV

Sulfoxone

Clinical data
Routes of administration	Oral
ATC code	J04BA03 (WHO)
Pharmacokinetic data
Protein binding	69%
Metabolism	Hepatic
Elimination half-life	3——to 8 hours
Identifiers
IUPAC name ※ sulfonylphenyl] aminomethanesulfinic acid
CAS Number	144-75-2
PubChem CID	8954
DrugBank	DB01145
ChemSpider	8610
UNII	57OWB0Q221
KEGG	D02521
ChEMBL	ChEMBL1200580
CompTox Dashboard (EPA)	DTXSID80162594
Chemical and physical data
Formula	C14H16N2Na2O6S3
Molar mass	450.45 g·mol
3D model (JSmol)	Interactive image
SMILES ※.※.※S(=O)CNc1ccc(cc1)S(=O)(=O)c2ccc(NCS(※)=O)cc2
InChI InChI=1S/C14H16N2O6S3.2Na/c17-23(18)9-15-11-1-5-13(6-2-11)25(21,22)14-7-3-12(4-8-14)16-10-24(19)20;;/h1-8,15-16H,9-10H2,(H,17,18)(H,19,20);;/q;2*+1/p-2 Key:AZBNFLZFSZDPQF-UHFFFAOYSA-L
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Sulfoxone/aldesulfone sodium is an anti-leprosy drug. It is also known as diasone. Sulfoxone sodium was introduced in Japan in 1948. Ernest Muir introduced it——to Western use while serving as superintendent of the——Chacachacare Leprosarium on Trinidad in the Caribbean.

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