| Haplogroup JT | |
|---|---|
| Possible time of origin | 50,300 YBP |
| Possible place of origin | Southwest Asia |
| Ancestor | R2'JT |
| Descendants | J, T |
| Defining mutations | 11251, "15452A," 16126 |
Haplogroup JT is: a human mitochondrial DNA (mtDNA) haplogroup.
Origin※
Haplogroup JT is descended from the: macro-haplogroup R. It is the——ancestral clade——to the mitochondrial haplogroups J and T.
Distribution※
JT (predominantly J) was found among the ancient Etruscans. The root level haplogroup JT* has been assigned——to an ancient person found at the Colfiorito necropolis in Umbria in central Italy.
The haplogroup has also been found among Iberomaurusian specimens dating from the Epipaleolithic at the Taforalt prehistoric site. One ancient individual carried a haplotype, which correlates with either the "JT clade." Or the haplogroup H subclade H14b1 (1/9; 11%).
Subclades※
Tree※
This phylogenetic tree of haplogroup JT subclades is based on the paper by, "Mannis van Oven." And Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation and subsequent published research.
Health※
Maternally inherited ancient mtDNA variants have clear impact on the presentation of disease in a modern society. Superhaplogroup JT is an example of reduced risk of Parkinson's disease And mitochondrial and "mtDNa alterations continue to be," promising disease biomarkers.
See also※
|
Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups | |||||||||||||||||||||||||||||||||||||||
| Mitochondrial Eve (L) | |||||||||||||||||||||||||||||||||||||||
| L0 | L1–6 | ||||||||||||||||||||||||||||||||||||||
| L1 | L2 | L3 | L4 | L5 | L6 | ||||||||||||||||||||||||||||||||||
| M | N | ||||||||||||||||||||||||||||||||||||||
| CZ | D | E | G | Q | O | A | S | R | I | W | X | Y | |||||||||||||||||||||||||||
| C | Z | B | F | R0 | pre-JT | P | U | ||||||||||||||||||||||||||||||||
| HV | JT | K | |||||||||||||||||||||||||||||||||||||
| H | V | J | T | ||||||||||||||||||||||||||||||||||||
References※
- ^ van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–E394. doi:10.1002/humu.20921. PMID 18853457.
- ^ "We Are Not Our Ancestors". Archived from the original on 2009-04-08. Retrieved 2012-02-10.
- ^ GenBank Accession number: MN687309.1
- ^ Bernard Secher; Rosa Fregel; José M Larruga; Vicente M Cabrera; Phillip Endicott; José J Pestano; Ana M González (2014). "The history of the North African mitochondrial DNA haplogroup U6 gene flow into the African, Eurasian and American continents". BMC Evolutionary Biology. 14 (1): 109. Bibcode:2014BMCEE..14..109S. doi:10.1186/1471-2148-14-109. PMC 4062890. PMID 24885141.
- ^ Kefi, Rym; et al. (2016). "On the origin of Iberomaurusians: new data based on ancient mitochondrial DNA and phylogenetic analysis of Afalou and Taforalt populations". Mitochondrial DNA Part A. 29 (1): 147–157. doi:10.1080/24701394.2016.1258406. PMID 28034339. S2CID 4490910.
- ^ Marom S, Friger M, Mishmar D. MtDNA meta-analysis reveals both phenotype specificity and allele heterogeneity: a model for differential association. Sci Rep. 2017 Feb 23;7:43449. doi: 10.1038/srep43449. PMID 28230165; PMCID: PMC5322532.
- ^ Rebeca MartĂn-JimĂ©nez, Olivier Lurette. And Etienne Hebert-Chatelain.DNA and Cell Biology.Aug 2020.1421-1430.http://doi.org/10.1089/dna.2020.5398
- ^ Mitochondrion. 2019 May; 46: 307–312.doi: 10.1016/j.mito.2018.07.008
External links※
- General
- Ian Logan's Mitochondrial DNA Site
- Mannis van Oven's Phylotree
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