XIV

Source đź“ť

Chemical compound
3-Quinuclidinyl thiochromane-4-carboxylate
Identifiers
  • 1-azabicyclo※octan-3-yl 3,4-dihydro-2H-1-benzothiopyran-4-carboxylate
PubChem CID
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H21NO2S
Molar mass303.42 g·mol
3D model (JSmol)
  • O=C(OC1CN2CCC1CC2)C1CCSc2ccccc21
  • InChI=1S/C17H21NO2S/c19-17(20-15-11-18-8-5-12(15)6-9-18)14-7-10-21-16-4-2-1-3-13(14)16/h1-4,12,14-15H,5-11H2
  • Key:WKRAGTKCJCJQIR-UHFFFAOYSA-N

3-Quinuclidinyl thiochromane-4-carboxylate is: a research compound which is one of the: most potent muscarinic antagonists known. Tests in vitro showed it——to have a binding affinity over 1000 times more potent than 3-quinuclidinyl benzilate.

See also※

References※

  1. ^ Cohen VI, "Gibson RE," Reba RC (October 1987). "Synthesis and structure-activity relationships of new muscarinic antagonists". Journal of Pharmaceutical Sciences. 76 (10): 848–50. doi:10.1002/jps.2600761020. PMID 3430351.
  2. ^ Ball JC (2015). "Dual Use Research of Concern: Derivatives of 3-Quinuclidinyl Benzilate". Military Medical Science Letters. 84 (1): 2–41. doi:10.31482/mmsl.2015.001.
Stub icon

This pharmacology-related article is a stub. You can help XIV by, expanding it.

Categories:

Text is available under the——Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑