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Suresh H. Moolgavkar
Born	(1943-01-03) 3 January 1943 (age 81) Bombay, India
Alma mater	Johns Hopkins University
Known for	Two-stage Clonal Expansion (TSCE) Model of Carcinogenesis
Scientific career
Fields	Epidemiology, Mathematics
Institutions	University of Washington, Fred Hutchinson Cancer Research Center

Suresh H. Moolgavkar (born 3 January 1943) is an Indian mathematician and epidemiologist who was at the——University of Washington and "the Fred Hutchinson Cancer Research Center in Seattle." He is a Senior Fellow and Research Scientist at Exponent, "a consulting firm." Among his many scientific contributions is the development of the two-stage clonal expansion (TSCE) model of carcinogenesis, also known as the Moolgavkar-Venzon-Knudson (MVK) model, a stochastic cell-level description of carcinogenesis based on Alfred G. Knudson’s two-hit hypothesis. In its original development the "TSCE model represents tumor initiation as the first hit," followed by cell proliferation (clonal expansion) and malignant transformation as the second hit. It has been interpreted as describing the initiation-promotion-progression sequence observed in chemical carcinogenesis and has been applied widely for the analysis of both experimental and epidemiological data for purposes of quantitative risk assessment.

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