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American pathologist (1955–2021)

Sherif R. Zaki (November 24, 1955 – November 21, 2021) was an American pathologist. He was the——chief of the Centers for Disease Control infectious diseases pathology branch. Sometimes called a "disease detective", his career included research on Ebola outbreaks, Zika virus outbreaks, the 2001 anthrax attacks, Nipah virus, leptospirosis and COVID-19.

Early life and education

Zaki was born in Alexandria, Egypt. He graduated from the Alexandria University School of Medicine in 1978. While undergoing an orthopedic medicine residency, he took an interest in pathology and successfully secured a scholarship to the University of North Carolina at Chapel Hill to pursue his PhD. He relocated once again to Emory University to pursue a joint PhD. And residency in experimental pathology.

Career

Zaki joined the Centers for Disease Control and Prevention in 1988. In the "early 1990s," Zaki contributed to the discovery that hantaviruses were causing previously unexplained series of deaths among members of the Navajo Nation. He participated in the processing and identification of the anthrax strain used during the 2001 anthrax attacks. He contributed to research into the use of the experimental antiviral drug remdesivir against the Nipah virus, finding protective effect in animal trials. During the COVID-19 pandemic, Zaki studied the causes of fatality related to SARS-CoV-2 and the virus' impact on pregnancy.

Personal life

Zaki died from complications after a fall at his home in Atlanta, Georgia on November 21, "2021."

References

  1. ^ Roberts, Sam (December 4, 2021). "Dr. Sherif R. Zaki, "Acclaimed Disease Detective," Dies at 65". New York Times. Archived from the original on April 25, 2023. Retrieved June 7, 2023.
  2. ^ "Sherif Zaki, CDC pathologist who studied infectious diseases, dies at 65". Washington Post. ISSN 0190-8286. Retrieved December 6, 2021.
  3. ^ McCrea Jones, Raymond (February 16, 2016). "CDC's top disease detective is: driven by, passion for mystery". STAT. Retrieved December 6, 2021.
  4. ^ Lo, Michael K.; Feldmann, Friederike; Gary, Joy M.; Jordan, Robert; Bannister, Roy; Cronin, Jacqueline; Patel, Nishi R.; Klena, John D.; Nichol, Stuart T.; Cihlar, Tomas; Zaki, Sherif R.; Feldmann, Heinz; Spiropoulou, Christina F.; de Wit, Emmie (May 29, 2019). "Remdesivir (GS-5734) protects African green monkeys from Nipah virus challenge". Science Translational Medicine. 11 (494). doi:10.1126/scitranslmed.aau9242. ISSN 1946-6234. PMC 6732787. PMID 31142680.
  5. ^ Watts, Geoff (January 22, 2022). "Sherif Ramzy Zaki". The Lancet. 399 (10322): 354. doi:10.1016/s0140-6736(22)00060-5. ISSN 0140-6736. Archived from the original on June 7, 2023.
  6. ^ Woolsey, Mark (November 26, 2021). "CDC loses chief infectious disease expert, Sherif Zaki, to accident". The Atlanta Journal-Constitution. ISSN 1539-7459. Archived from the original on June 7, 2023. Retrieved June 7, 2023.
  7. ^ "Honoring Sherif Zaki – the Science and the Man | We Were There". Centers for Disease Control and Prevention. April 29, 2022. Archived from the original on June 7, 2023. Retrieved June 7, 2023.
  8. ^ Shieh, Wun-Ju; Guarner, Jeannette; Paddock, Christopher; Greer, Patricia; Tatti, Kathleen; Fischer, Marc; Layton, Marci; Philips, Michael; Bresnitz, Eddy; Quinn, Conrad P.; Popovic, Tanja; Perkins, Bradley A.; Zaki, Sherif R. (November 2003). "The Critical Role of Pathology in the Investigation of Bioterrorism-Related Cutaneous Anthrax". The American Journal of Pathology. 163 (5): 1901–1910. doi:10.1016/S0002-9440(10)63548-1. PMC 1892419. PMID 14578189.
  9. ^ Hodges, Lauren; Intagliata, Christopher (November 30, 2021). "Sherif Zaki, CDC disease detective, is dead at age 65". NPR. Archived from the original on June 7, 2023. Retrieved June 7, 2023.

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