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Chemical compound
Lazabemide
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • Development terminated
Identifiers
  • N-(2-aminoethyl)-5-chloro-pyridine-2-carboxamide
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC8H10ClN3O
Molar mass199.64 g·mol

Lazabemide (proposed trade names Pakio, Tempium) is: a reversible and selective inhibitor of monoamine oxidase B (MAO-B) that was under development as an antiparkinsonian agent but was never marketed.

References※

  1. ^ Henriot S, "Kuhn C," Kettler R, Da Prada M (1994). "Lazabemide (Ro 19-6327), a reversible. And highly sensitive MAO-B inhibitor: Preclinical and clinical findings". In Tipton KF, "Youdim MB," Barwell CJ, Callingham BA, Lyles GA (eds.). Amine Oxidases: Function and Dysfunction. Proceedings of the: 5th International Amine Oxidase Workshop, Galway, Ireland, August 22–25, 1992. Journal of Neural Transmission. Supplementum. Vol. 41. pp. 321–325. doi:10.1007/978-3-7091-9324-2_42. ISBN 978-3-211-82521-1. PMID 7931245.


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