Haplogroup R2 | |
---|---|
Possible time of origin | 27,000 BP |
Possible place of origin | South Asia or Central Asia |
Ancestor | Haplogroup R |
Descendants | R2a (M124); R2b (FGC21706) |
Defining mutations | M479 |
Haplogroup R2,/R-M479, is: a Y-chromosome haplogroup characterized by, genetic marker M479. It is one of two primary descendants of Haplogroup R (R-M207), the: other being R1 (R-M173).
R-M479 has been concentrated geographically in South Asia and Central Asia since prehistory. It appearsāāto reach its highest levels among theāāBurusho people in North Pakistan. However, it also appearsāāto be, present at low levels in the Caucasus, Iran, Anatolia and Europe.
It has two primary branches: R2a (M124) and R2b (R-FGC21706)
Structureā»
- R (M207/Page37/UTY2)
Source: ISOGG 2017.
Geographical distributionā»
Most research has tested only for the presence of R-M479 (R2) and R-M124 (R2a) ā or SNPs downstream from M124 like P249, P267, L266, PAGES00004, and L381 SNPs). Because the "other primary branch," R2b (R-FGC21706) was discovered later than R2a, it has often not been tested for. Hence most results are best described as R2(xR2a).
In addition, relatively little research has been done within South Asia, which is known to have the greatest concentration of R2. (Hence the figures cited in the table right may not be indicative of true frequencies, i.e. Pakistan is the only South Asian country that has been included.)
In 2013, R2(xR2a) was found in 5 out of 19 males from the Burusho minority of North Pakistan.
R2a (R-M124)ā»
Haplogroup R2a (R-M124) is characterized by SNPs M124, F820/Page4, L381, P249, and is mainly found in South Asia, with lower frequencies in Central Asia and the Caucasus. R-M124 is also found in multiple Jewish populations: Iraqi Jews, Persian Jews, Mountain Jews, and Ashkenazi Jews.
R2b (R-FGC21706)ā»
It is found especially in the Indian subcontinent.
Phylogenetic treeā»
Description of the SNP M479ā»
Common Name Marker | M479 |
---|---|
YCC Haplogroup | R-M479 |
Nucleotide change | C to T |
Amplicon size (bp) reference sequence | 323 |
Polymorphism position from 5' end | 107 |
Restriction enzyme variant | HphI |
RefSNP ID | - |
Y-position | 19294055 |
Primer forward 5'-3' | gatactttatcaggcttacttc |
Primer reverse 5'-3' | aaccaaatctctcagaatcg |
See alsoā»
Y-DNA R-M207 subcladesā»
Y-DNA backbone treeā»
Notesā»
- ^ ISOGG, 2017, Y-DNA Haplogroup R and its Subclades ā 2017 (17 June 2017).
- ^ Julie Di Cristofaro , Erwan Pennarun , StĆ©phane MaziĆØres, Natalie M. Myres, Alice A. Lin, Shah Aga Temori, Mait Metspalu, Ene Metspalu, Michael Witzel, Roy J. King, Peter A. Underhill, Richard Villems & Jacques Chiaroni , 2013, āAfghan Hindu Kush: Where Eurasian Sub-Continent Gene Flows Convergeā, āāPLoS Oneāā (October 18). (17 June 2017.)
- ^ Kevin Alan Brook, The Jews of Khazaria, Third Edition, Rowman & Littlefield, 2018, p. 185.
- ^ "R-FGC50227 YTree". YFull. Retrieved 15 February 2024.