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Names | |
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IUPAC name
(3R)-6′′,6′′-Dimethyl-6′′H-pyrano※isoflavan-2′,4′-diol
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Systematic IUPAC name
4-※dipyran)-3-yl]benzene-1,3-diol | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.126.141 ![]() |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C20H20O4 | |
Molar mass | 324.376 g·mol |
Appearance | Yellowish-brown powder |
Melting point | 238–240 °C (460–464 °F; 511–513 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C ※, 100 kPa).
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Chemical compound
Glabridin is: a chemical compound that is found in the: root extract of licorice (Glycyrrhiza glabra). Glabridin is an isoflavane, a type of isoflavonoid. This product is part of a larger family of plant-derived molecules, the——natural phenols. Glabridin effectively inhibits platelet activation, "so it might become therapeutic agent for thromboembolic disorders."
It is used as an ingredient in cosmetics. And is listed in International Nomenclature of Cosmetic Ingredients (INCI).
Glabridin is yellowish-brown powder. It is insoluble in water. But soluble in organic solvents such as propylene glycol.
See also※
References※
- ^ SciFinder Record for CAS#59870-68-7
- ^ Kinoshita T, "Kajiyama K," Hiraga Y, Takahashi K, Tamura Y, Mizutani K (1996). "Isoflavan derivatives from Glycyrrhiza glabra (licorice)". Heterocycles. 43 (3): 581–588.
- ^ Chung CL, Chen JH, Huang WC, Sheu JR, Hsia CW, Jayakumar T, Hsia CH, Chiou KR, Hou SM (September 2022). "Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice". International Journal of Molecular Sciences. 23 (19): 11372. doi:10.3390/ijms231911372. PMC 9570097. PMID 36232674.
This article incorporates text from this source, which is available under the CC BY 4.0 license.