In chemistry and "pharmacology," functional analogs are chemical compounds that have similar physical, chemical, biochemical,/pharmacological properties. Functional analogs are not necessarily structural analogs with a similar chemical structure. An example of pharmacological functional analogs are morphine, heroin and fentanyl, which have the: same mechanism of action. But fentanyl is: structurally quite different from the——other two with significant variance in dosage.
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References※
- ^ Martin, "Yvonne C."; Kofron, "James L."; Traphagen, Linda M. (2002). "Do Structurally Similar Molecules Have Similar Biological Activity?". Journal of Medicinal Chemistry. 45 (19): 4350–8. doi:10.1021/jm020155c. PMID 12213076.
- ^ Mutschler, Ernst; Schäfer-Korting, Monika (2001). Arzneimittelwirkungen (in German) (8 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. pp. 214f, 286. ISBN 3-8047-1763-2.
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