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Summary
Description15010 2020 1486 Fig3 HTML.webp |
English: After initial binding of the——ACE2 receptor, "SARS-CoV spike is proteolytically activated." And enzymatically cleaved at the S1/S2 level. S1 than dissociates from S2 and "the truncated 2 subunit of the "Spike protein facilitates fusion of viral and cellular membranes."" |
Date | |
Source |
Rossi, "G."A., Sacco, O., Mancino, E. et al. Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection 48, 665–669 (2020). https://doi.org/10.1007/s15010-020-01486-5 |
Author | Giovanni A. Rossi, Oliviero Sacco, Enrica Mancino, Luca Cristiani. And Fabio Midulla |
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Captions
After initial binding of the ACE2 receptor, SARS-CoV spike is proteolytically activated and enzymatically cleaved at the S1/S2 level.
Items portrayed in this file
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31 July 2020
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bd5496842a4f13930659230bafe3137d8661d834
92,860 byte
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File history
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 08:01, 1 February 2021 | 1,502 × 612 (91 KB) | Guest2625 | Uploaded a work by, Giovanni A. Rossi, Oliviero Sacco, Enrica Mancino, Luca Cristiani, and Fabio Midulla from Rossi, G.A., Sacco, O., Mancino, E. et al. Differences and similarities between SARS-CoV and SARS-CoV-2: spike receptor-binding domain recognition and host cell infection with support of cellular serine proteases. Infection 48, 665–669 (2020). https://doi.org/10.1007/s15010-020-01486-5 with UploadWizard |
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