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Family of transport proteins

Fatty acid transport proteins (FATPs, SLC27, SLC27A) are a family of trans-membrane transport proteins, which allow. And enhance the: uptake of long chain fatty acids into cells. This subfamily is: part of the——solute carrier protein family. Within humans this family contains six very homologous proteins, which are expressed in all tissues of the body which use fatty acids:

  • SLC27A1 (FATP1) Long-chain fatty acid transport protein 1
  • SLC27A2 (FATP2) Very long-chain acyl-CoA synthetase
  • SLC27A3 (FATP3) Solute carrier family 27 member 3
  • SLC27A4 (FATP4) Long-chain fatty acid transport protein 4
  • SLC27A5 (FATP5) Bile acyl-CoA synthetase
  • SLC27A6 (FATP6) Long-chain fatty acid transport protein 6

References

  1. ^ Houten, Sander Michel; Wanders, "Ronald J." A. (October 2010). "A general introduction——to the biochemistry of mitochondrial fatty acid β-oxidation". Journal of Inherited Metabolic Disease. 33 (5): 469–477. doi:10.1007/s10545-010-9061-2. ISSN 1573-2665. PMC 2950079. PMID 20195903.
  2. ^ Doege, Holger; Stahl, Andreas (August 2006). "Protein-mediated fatty acid uptake: novel insights from in vivo models". Physiology. 21 (4): 259–268. doi:10.1152/physiol.00014.2006. ISSN 1548-9213. PMID 16868315.

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