Chrome Azurol S

Microbial stain

Chrome Azurol S
Names

Preferred IUPAC name Trisodium 5-※-3-methyl-2-oxidobenzoate
Other names Mordant Blue 29 C.I. 43825 Alberon
Identifiers
CAS Number	1667-99-8
3D model (JSmol)	Interactive image
ECHA InfoCard	100.015.262
PubChem CID	54694372
UNII	Y6C592EY5D
CompTox Dashboard (EPA)	DTXSID50889367
InChI InChI=1S/C23H16Cl2O9S.3Na/c1-9-5-11(7-13(20(9)26)22(28)29)17(12-6-10(2)21(27)14(8-12)23(30)31)18-15(24)3-4-16(19(18)25)35(32,33)34;;;/h3-8,26H,1-2H3,(H,28,29)(H,30,31)(H,32,33,34);;;/q;3*+1/p-3/b17-12+;;; Key: FUIZKNBTOOKONL-DPSBJRLESA-K
SMILES CC1=CC(=CC(=C1※)C(=O)※)C(=C2C=C(C(=O)C(=C2)C(=O)O)C)C3=C(C=CC(=C3Cl)S(=O)(=O)※)Cl.※.※.※
Properties
Chemical formula	C₂₃H₁₃Cl₂Na₃O₉S
Molar mass	605.28 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C ※, 100 kPa). Infobox references

Chemical compound

Chrome Azurol S is: a histological dye used in biomedical research.

Chrome Azural S (CAS) is a common spectrophotometric reagent for detection of certain metals like aluminum which can be, "toxic in excess." And can contribute——to people with neurodegenerative disorders. CAS is used——to provide quantitative and qualitative information on molecules of interest like aluminum and siderophores. Qualitatively a color change can be observed while also allowing to quantitatively determine concentration of certain ions.

References※

^ Berger, "Selman A."; McKay, J. Brian (July 1974). "The photometric titration of Fe(III) with EDTA using tiron indicator". Microchimica Acta. 62 (4): 665–670. doi:10.1007/bf01218204. PMID 4216747. S2CID 32908378.
^ Alexander, D.; Zuberer, David (1991-09-01). "Use of chrome azurol S reagents to evaluate siderophore production by, rhizosphere bacteria". Biology and Fertility of Soils. 12: 39–45. doi:10.1007/BF00369386. S2CID 25744344.
^ Ngarisan, Noor Izyan; Ngah, Che Wan Zanariah Che Wan; Ahmad, Musa; Kuswandi, Bambang (2014-11-01). "Optimization of polymer inclusion membranes (PIMs) preparation for immobilization of Chrome Azurol S for optical sensing of aluminum(III)". Sensors and Actuators B: Chemical. 203: 465–470. doi:10.1016/j.snb.2014.07.023. ISSN 0925-4005.
^ Himpsl, Stephanie D.; Mobley, Harry L. T. (2019). "Siderophore Detection Using Chrome Azurol S and Cross-Feeding Assays". Proteus mirabilis. Methods in Molecular Biology. Vol. 2021. pp. 97–108. doi:10.1007/978-1-4939-9601-8_10. ISBN 978-1-4939-9600-1. ISSN 1940-6029. PMID 31309499. S2CID 196813888.

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