Bethanidine

Chemical compound

Bethanidine
Clinical data

ATC code	C02CC01 (WHO)
Identifiers
IUPAC name 3-benzyl-1,2-dimethylguanidine
CAS Number	55-73-2
PubChem CID	2368
IUPHAR/BPS	7618
DrugBank	DB00217
ChemSpider	2278
UNII	W8S3YM7AUU
KEGG	D01603
ChEBI	CHEBI:37937
ChEMBL	ChEMBL1201260
CompTox Dashboard (EPA)	DTXSID7022677
Chemical and physical data
Formula	C₁₀H₁₅N₃
Molar mass	177.251 g·mol
3D model (JSmol)	Interactive image
SMILES N(=C(/NCc1ccccc1)NC)\C
InChI InChI=1S/C10H15N3/c1-11-10(12-2)13-8-9-6-4-3-5-7-9/h3-7H,8H2,1-2H3,(H2,11,12,13) Key:NIVZHWNOUVJHKV-UHFFFAOYSA-N
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Bethanidine (or betanidine) is a sympatholytic drug.

References※

Central

α₂-Adrenergic receptor agonists	Clonidine Guanabenz Guanfacine Guanoxabenz Methyldopa Tiamenidine
Adrenergic release inhibitors	Bethanidine Bretylium Debrisoquine Guanadrel Guanazodine Guancydine Guanethidine Guanoclor Guanoxan
Imidazoline receptor agonists	Moxonidine Rilmenidine Tolonidine
Ganglion-blocking/nicotinic antagonists	Hexamethonium Mecamylamine Pentolinium Trimethaphan

Peripheral

Indirect

Monoamine oxidase inhibitors	Pargyline
VMAT inhibitors	Bietaserpine Deserpidine Methoserpidine Reserpine Syrosingopine
Tyrosine hydroxylase inhibitors	Metirosine

Direct

α₁-Adrenergic receptor blockers	Doxazosin Ketanserin Indoramin Prazosin Trimazosin Urapidil
Non-selective α-adrenergic receptor blockers	Phentolamine

Serotonin receptor antagonists	Ketanserin Lidanserin
Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension)	dual (Aprocitentan, Bosentan, Macitentan (+tadalafil)) selective (Ambrisentan, Sitaxentan)

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